KMID : 0374920080290010101
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Inje Medical Journal 2008 Volume.29 No. 1 p.101 ~ p.106
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A case of delayed central fever with rhabdomyolysis after removal of pituitary tumor
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Jang Je-Hyeok
Choi Gyu-Nam Kim Il-Hwan Nho Eun-Ji Kim Yoon-Jung Ryu Choong-Heon Ko Jung-Hae Park Bong-Su Kim Tae-Kyoon Kwon Min-Jeong Lee Soon-Hee Park Jeong-Hyun
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Abstract
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Body temperature is controlled by thermoregulatory center of the hypothalamus. We report a case of 24 years old man with central fever. He was subjected to a partial excision of pituitary tumor compressing optic chiasm four years ago. He has received hormonal therapy for panhypothyroidism after removal of pituitary tumor. And He received gamma knife operation for partially contrast-enhancing masses in suprasellar and both hypothalamic areas that is probably postoperatively remnant or recurrent tumor of pituitary adenoma. One year after gamma knife operation, he presented with a febrile syndrome of unknown origin including rhabdomyolysis. All usual investigations proved negative. We diagnosed him as central fever with rhabdomyolysis. He received medical ICU care with cooling bed, ice pack. And his symptom improved. Postoperative hyperthermia may result following resection of the pituitary tumor. When central fever is suspected taking note of past history, a quick recognition of course of fever can help reduce the using of unnecessary antibiotics and hospital stay.
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KEYWORD
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central fever, pituitary adenoma, hypothalamic dysfunction
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